Open Journal

Russian Open Medical Journal

In experiments in non‐inbred rats, it has been established that chronic intoxication of ethanol (30 days, total dose – 6.0 LD50) essentially reduces concentration of cytokines IFNγ, IL‐2, IL‐4, IL‐10 in blood, increases concentration of IL‐6, reduces an interrelation IFNγ/IL‐4 in comparison with the control, suppresses of immune responses, which displays the greater le...

Russian Open Medical Journal

The objective of the research is to study the role of polymorphic gene variants of Tumor Necrosis Factor‐α (TNFA), Bcl‐2‐ associated X protein (BAX), p53 Binding Protein (MDM2), vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in the development of chronic lymphocytic leukemia (CLL). Methods: The comparative analysis of allele and...

Burns Open journal.

Russian Open Medical Journal

Background — The presence of chronic hard-to-heal wounds significantly affects patients’ quality of life causing pain, discomfort, decrease of mobility and consequently leads to social isolation and depression. This type of wound is more prevalent among older population. It has been estimated that up to 1-2% of the world population have this condition. The treatment of hard-to-heal wounds is ex...

Russian Open Medical Journal

Developmental anomalies in the origin and branching pattern of the external carotid artery are not common. The level of the bifurcation of the common carotid artery and also the variations in the origin/branching pattern of the external carotid artery are well known and documented. During a routine dissection of middle aged male cadaver in Department of anatomy of BP Koirala Institute...